5 Easy Facts About NAD+ and Sirtuins relationship explained Described
Upcoming, we treated cells with unique concentrations of NAD+. When added for twenty-four h at 80 µM in HeLa and 400 µM in U2OS cells, NAD+ impaired the incorporation of EdU (Fig. 2a and Prolonged Facts Fig. 1k,l). Also, sixteen µM of NAD+ was ample to cut back fork pace by ~forty% in HeLa cells without affecting the full degree of DNA s